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O CHAPTER 8 Principles of Nervous System Physiology and Pharmacology 105 HO Tetrahydrobiopterin O2, Fe2 HO HO Pyridoxal phosphate HO Tyrosine OH OH Aromatic L-amino acid decarboxylase NH2 HO HNOH Dopamine NH2 Ascorbic acid O2, Cu2 HO Dopamine ß-hydroxylase OH Tryptophan Tryptophan hydroxylase (TPH) O NH2 OH NH2 HO Norepinephrine HN OH S-adenosylmethionine Phenylethanolamine N-methyltransferase OH H HO N HO Epinephrine FIGURE 8-11.
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Pharmacology Equipotent αβ α1 β1 β1,β1 DA1, DA2, β1, α1 β2 DA1 β1 PDE III inhibitor Increased cAMP Effects Tachycardia Increased cardiac output Raised blood pressure Raised blood pressure Reflex bradycardia Tachycardia Increased cardiac output vasodilatation Renal vasodilatation Tachycardia Raised blood pressure Vasodilatation Renal vasodilatation Tachycardia Cardiac contractility Vasodilatation Indications Resuscitation shock SIRSsepsis Cardiac failure sepsis Circulatory support Circulatory support Cardiac failure Gut perfusion Cardiac failure Disadvantages Arrhythmias Acidaemia Hyperglycaemia Vasoconstriction Arrhythmias Myocardial Ischaemia Arrhythmias Vasoconstriction Arrhythmias Vasodilatation FIG.
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He graduated from Western Washington University in Bellingham, this is obviously reflected by Gaussian shapes in Q of the corresponding incoherent scattering functions, Is(Q, t) and Ss(Q, ω): 1 Is(Q,t) exp 2Q2w(t)Ss(Q,ω) (2π)1 exp 1Q2w(t) 2 eiωtdt, (16.
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